One of three research pillars at the Wu Tsai Institute, the Center for Neurocomputation and Machine Intelligence advances understanding of human cognition by integrating data science, computer science, applied math, and engineering into the analysis and modeling of neuroscience data. The mathematical, statistical, and computational tools of these fields provide a common language to bridge the many branches of neuroscience and derive abstract principles of cognition. In turn, these theories generate hypotheses about brain mechanisms that can be tested experimentally and incorporated into artificial systems.